Morphology of Characteristic Particles Associated with Avian Erythroblastosis.

Abstract

A particulate component, which may be the etiological virus, was isolated by ultracentrifugation of the blood plasma of chickens with erythroblastosis. The particles were of spheroidal shape and variable size, averaging approximately 102 m[mu] diameter. Micographs of unshadowed preparations showed ciruclar images of an appearance suggesting that the particles consisted predominantly of a watery, low-electron contrast, gel-like material surrounding a small relatively dense internal structure. Findings were compared with those obtained in the analogous studies of particles representing the virus of myeloblastosis and that of one form of lymphomatosis.