Basic problems in interaction assessment.
Open Access
- 1 December 1993
- journal article
- review article
- Published by Environmental Health Perspectives in Environmental Health Perspectives
- Vol. 101 (suppl 4), 59-66
- https://doi.org/10.1289/ehp.93101s459
Abstract
This paper reviews problems with the definition and estimation of interactions in epidemiologic studies. Methods for modeling interactions and dose-response also are reviewed, and references to more detailed literature are provided. Concepts are illustrated in the context of evaluating the joint effects of household radon exposure and environmental tobacco smoke.Keywords
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