X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations
- 5 March 1999
- journal article
- research article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 286 (4), 1147-1159
- https://doi.org/10.1006/jmbi.1998.2533
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Structure-Based Thermodynamic Analysis of HIV-1 Protease InhibitorsBiochemistry, 1997
- Potent and Orally Bioavailable HIV-1 Proteinase Inhibitors Containing the 2-aminobenzylstatine MoietyAntiviral Chemistry and Chemotherapy, 1995
- Flap opening in HIV-1 protease simulated by ‘activated’ molecular dynamicsNature Structural & Molecular Biology, 1995
- HIV proteinase inhibitors containing 2-aminobenzylstatine as a novel scissile bond replacement: biochemical and pharmacological characterizationAntiviral Research, 1994
- Crystal structures of HIV-1 protease-inhibitor complexesPerspectives in Drug Discovery and Design, 1993
- Experimentally verifying molecular dynamics simulations through fluorescence anisotropy measurementsBiochemistry, 1991
- Purification, Assay and Kinetic Features of HIV-1 ProteinaseBiological Chemistry Hoppe-Seyler, 1990
- Kinetic Ising model for polymer dynamics. II. Generalized transition rates and the Williams–Watts nonexponential functionThe Journal of Chemical Physics, 1985
- Molecular dynamics with coupling to an external bathThe Journal of Chemical Physics, 1984
- Analysis of time-resolved fluorescence anisotropy decaysBiophysical Journal, 1984