Enzymatic properties and sensitivity to inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with Glu-138→Arg and Tyr-188→His mutations
- 31 May 1994
- journal article
- Published by Elsevier in Antiviral Research
- Vol. 24 (1), 43-57
- https://doi.org/10.1016/0166-3542(94)90051-5
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Review of HIV-1 reverse transcriptase three-dimensional structure: Implications for drug designPerspectives in Drug Discovery and Design, 1993
- A nonnucleoside reverse transcriptase inhibitor active on human immunodeficiency virus type 1 isolates resistant to related inhibitorsAntimicrobial Agents and Chemotherapy, 1993
- U-90152, a potent inhibitor of human immunodeficiency virus type 1 replicationAntimicrobial Agents and Chemotherapy, 1993
- HIV‐1‐specific RT inhibitors: Highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptaseMedicinal Research Reviews, 1993
- Use of evolutionary limitations of HIV-1 multidrug resistance to optimize therapyNature, 1993
- HIV-1-Specific Reverse Transcriptase Inhibitors Show Differential Activity against HIV-1 Mutant Strains Containing Different Amino Acid Substitutions in the Reverse TranscriptaseVirology, 1993
- Purification, characterization and crystallization of recombinant HIV-1- reverse transcriptaseJournal of Chromatography A, 1992
- Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an InhibitorScience, 1992
- Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase: Nevirapine as a Prototype DrugAIDS Research and Human Retroviruses, 1992
- Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase InhibitorScience, 1990