Results of 89 Strontium Therapy in Patients with Carcinoma of the Prostate and Incurable Pain from Bone Metastases: A Preliminary Report
- 1 December 1976
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 116 (6), 764-768
- https://doi.org/10.1016/s0022-5347(17)59002-3
Abstract
The therapeutic application of 89Sr for the relief of pain in 11 cases of carcinoma of the prostate with skeletal metastases is reported. A significant clinical improvement could be observed in 8 of the 11 patients, with generalized osseous metastases of prostatic carcinoma after the application of 30 .mu.Ci 89Sr/kg. The effect was long lasting. An increase of alkaline phosphatase was observed, which was interpreted as an indication of the reactivation of osteoblasts and osteoid peripheral zones owing to .beta.-emission of the radioisotope in the affected areas. The indications for such therapy are discussed.This publication has 9 references indexed in Scilit:
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