The clinical relevance of ferritin concentration in the cerebrospinal fluid.
Open Access
- 1 April 1981
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 44 (4), 329-333
- https://doi.org/10.1136/jnnp.44.4.329
Abstract
By means of a new technique (Particle Counting Immunoassay), we have determined the level of ferritin in 470 samples of cerebrospinal fluid of patients with various neurological disorders. The median value obtained in a control group was 2.3 ng/ml with an upper limit at 5.5 ng/ml. the concentrations in the serum and cerebrospinal fluid were independent, but that in cerebrospinal fluid correlated with its total protein content. High values of ferritin were found in infectious meningo-encephalitis, in vascular diseases of the central nervous system, and, unexpectedly, in several cases of dementia without obvious vascular pathology.This publication has 11 references indexed in Scilit:
- Cerebrospinal fluid ferritin in patients with cerebral infarction or bleedingActa Neurologica Scandinavica, 2009
- Particle counting immunoassay (PACIA)—VI. The determination of rabbit IgG antibodies against myelin basic protein using IgM rheumatoid factorMolecular Immunology, 1981
- Automated particle-counting immunoassay for alpha-fetoprotein.Clinical Chemistry, 1981
- Particle counting immunoassay. IV. The use of F(ab′)2 fragments and Nϵ-chloroacetyl lysine N-carboxyanhydride for their coupling to polystyrene latex particlesJournal of Immunological Methods, 1979
- Particle counting immunoassay (Pacia). I. A general method for the determination of antibodies, antigens, and haptensJournal of Immunological Methods, 1977
- Ferritin in SerumNew England Journal of Medicine, 1975
- Determination of total protein in spinal fluid with sulphosalicylic acid and trichloroacetic acidClinica Chimica Acta; International Journal of Clinical Chemistry, 1960
- THE NON‐HAEMIN IRON IN THE CEREBRAL CORTEX IN ALZHEIMER'S DISEASEJournal of Neurochemistry, 1960
- Alzheimer's disease; a clinico-pathologic analysis of twenty-three cases with a theory on pathogenesis.1953
- ALZHEIMERʼS DISEASEJournal of Nervous & Mental Disease, 1953