Increased frequency of chromosome aberrations in workers exposed to styrene.

Abstract

Chromosomal aberrations in lymphocytes from peripheral blood were significantly more frequent in 6 workers from a plant manufacturing polyester resin boats (average 10.8/100 cells) than in 6 age- and sex-matched controls (5.2/100 cells). The contamination of the workroom air with styrene, as measured on 3 occasions within 3 yr in different areas of the plant, was 50-400 mg/m3.