Specificity and reactivity of cytoplasmic and nucleolar antibody in SLE sera
Open Access
- 1 June 1969
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 12 (3), 173-180
- https://doi.org/10.1002/art.1780120303
Abstract
The serum of 2 of 31 patients with SLE was found to contain an antibody to a previously unrecognized RNA‐containing antigen found in human mononuclear cell cytoplasm and nucleolus. When tissue fixed, this antibody proved capable of fixing the patient's own rheumatoid factor and human complement components. No recognizable inhibition of complement fixation by rheumatoid factor could be demonstrated by the fluorescent antibody technic.This publication has 18 references indexed in Scilit:
- The clinical significance of titered antinuclear antibodiesArthritis & Rheumatism, 1967
- Precipitating antibodies to ribosomes in the serum of patients with systemic lupus erythematosusImmunochemistry, 1967
- REACTION OF ANTINUCLEAR FACTORS WITH POLYMORPHONUCLEAR GRANULOCYTESActa Pathologica Microbiologica Scandinavica, 1967
- “Bywater' Hooks”Arthritis & Rheumatism, 1967
- Effects of rheumatoid factor on complement levels in vivoArthritis & Rheumatism, 1966
- A hypothetical common mechanism in systemic lupus erythematosus and rheumatoid arthritisArthritis & Rheumatism, 1966
- AUTO‐ANTILEUKOCYTE RIBOSOMAL FRACTION IN LEUKONEUTROPENIASAnnals of the New York Academy of Sciences, 1965
- INHIBITION OF COMPLEMENT FIXATION BY RHEUMATOID SERA*Annals of the New York Academy of Sciences, 1965
- Articular manifestations in primary hyperparathyroidismArthritis & Rheumatism, 1962
- Anti‐cytoplasmic factors in the sera of patients with systemic lupus erythematosus and certain other diseasesArthritis & Rheumatism, 1960