Activation of c-myb expression by phytohemagglutinin stimulation in normal human T lymphocytes.
Open Access
- 1 October 1985
- journal article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 5 (10), 2874-2877
- https://doi.org/10.1128/mcb.5.10.2874
Abstract
The expression of c-myb in normal human T lymphocytes directly derived from a normal subject and not adapted to continuous growth in culture was found to be markedly increased after phytohemagglutinin stimulation. In the same cells, the expression of c-myc mRNA is a much earlier event compared with the appearance of c-myb mRNA, which takes place soon after that of histone H3 mRNA. The increase in c-myb expression was not due to a particular T-lymphocyte subset, as shown by in situ hybridization assays.Keywords
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