Abstract
Drying and freezing are identical in their effects on the formation of lactic acid in amphibian muscle. The peak of the production curve which occurs at[long dash]2.2[degree] to[long dash]2.5[degree] C. or 79% water removal is apparently coincident with the point at which instantaneous death occurs in the muscle. These 2 events cannot be associated with a sudden change in the concentration of any constituent of the plasma of which the behavior in physiological solution is known.

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