Some Aspects of the Pharmacology of Orphenadrine
- 1 September 1963
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 15 (1), 329-336
- https://doi.org/10.1111/j.2042-7158.1963.tb12790.x
Abstract
Orphenadrine possesses muscle-relaxant activity resembling that of tubocurarine in preparations of the hen, rat and frog. It antagonises suxamethonium-induced contracture in the hen but increases the duration of depression of the twitch height. The bearing of these findings upon the anti-Parkinson's activity and other uses of orphenadrine is discussed.Keywords
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