THE PROTEIN TOLERANCE OF VERY LOW BIRTH WEIGHT INFANTS FED HUMAN MILK PROTEIN ENRICHED MOTHER'S MILK

Abstract
Pooled breast milk was ultra-filtrated and freeze-dried to give a product with a protein content of 60 g/100 g powder. More than half of the secretory IgA activity against Escherichia coli O antigen was preserved. This concentrated protein was added to the mother''s fresh milk providing a protein supply of 3.0-3.5 g/kg per 24 h in 4 VLBW [very low birth weight] infants, at a calorie supply of 110 kcal/kg per 24 h. Growth followed the intrauterine rate. Free amino acid levels, acid-base balance and urea concentrations of peripheral whole blood indicated tolerance of the increased supply of human milk protein.