TOPS‐MODE Approach for the Prediction of Blood–Brain Barrier Permeation
- 1 July 2004
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical Sciences
- Vol. 93 (7), 1701-1717
- https://doi.org/10.1002/jps.20081
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Modeling Blood-Brain Barrier Partitioning Using the Electrotopological StateJournal of Chemical Information and Computer Sciences, 2002
- Computational approaches to the prediction of the blood–brain distributionAdvanced Drug Delivery Reviews, 2002
- High-Throughput Prediction of Blood−Brain Partitioning: A Thermodynamic ApproachJournal of Chemical Information and Computer Sciences, 2000
- Predicting Blood−Brain Barrier Permeation from Three-Dimensional Molecular StructureJournal of Medicinal Chemistry, 2000
- Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood–brain barrier penetrationJournal of Pharmaceutical Sciences, 1999
- Estimation of Blood-Brain Barrier Crossing of Drugs Using Molecular Size and Shape, and H-Bonding DescriptorsJournal of Drug Targeting, 1998
- On the Partition of Ampholytes: Application to Blood–Brain DistributionJournal of Pharmaceutical Sciences, 1997
- Animal models for studying transport across the blood-brain barrierJournal of Neuroscience Methods, 1995
- Hydrogen Bonding. 33. Factors That Influence the Distribution of Solutes between Blood and BrainJournal of Pharmaceutical Sciences, 1994
- Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonistsJournal of Medicinal Chemistry, 1988