Mycoplasma pneumoniae Infection: Role of a Surface Protein in the Attachment Organelle
- 16 April 1982
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 216 (4543), 313-315
- https://doi.org/10.1126/science.6801766
Abstract
Attachment of Mycoplasma pneumoniae to host cell by means of a specialized terminus initiates infection. Monoclonal antibodies to a surface protein (Pl) inhibit this process, and react with a region of the tip covered with peplomer-like particles. Since antibodies against the Pl protein are generated by natural and experimental infection and by immunization, the substance may be an important determinant of protective immunity.Keywords
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