DIRECT RADIOIMMUNOASSAY OF HUMAN RENIN
- 1 June 1979
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 48 (6), 1041-1043
- https://doi.org/10.1210/jcem-48-6-1041
Abstract
Antibodies were raised in rabbit against pure human renin. The antisera obtained are highly specific for human renin versus hog, dog and rat renin. They do not cross-react with acid proteases such as pepsin and human cathepsin D. A direct radioimmunoassay is described for human renin in plasma and kidney extracts. 30 to 50 pg of enzyme (2.5 to 4 × 10−5 Goldblatt units) are detected.Keywords
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