Lipid Rafts As a Membrane-Organizing Principle

Abstract

Lipid Rafts Come of Age: Living cells are surrounded by cellular membranes composed of lipids and proteins. Much attention has been paid to the biogenesis and sorting of membrane proteins. The dynamics and sorting of lipids have been much more difficult to study. Lingwood and Simons (p. 46 ) review the evidence for, and the role played by, so-called lipid rafts—laterally segregated regions within membranes enriched for particular lipids and proteins.