Isolated interferonα‐receptor complexes stabilized in vitro
- 30 May 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 156 (1), 157-160
- https://doi.org/10.1016/0014-5793(83)80268-3
Abstract
We describe the extraction and stabilization in vitro of discrete complexes of interferon and cellular receptor proteins. A homogeneous complex of Mr 230000 was extracted at the time of peak receptor binding (30 min). Complex formation was specific for human interferon. At later times a second complex could also be extracted suggesting transfer of interferon to a second siteKeywords
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