Cop 1 Therapy for Multiple Sclerosis

Abstract

Multiple sclerosis is an inflammatory disease of the central nervous system in which infiltrating lymphocytes (predominantly T cells) and macrophages lead to degradation of the myelin sheath. The leading hypothesis about the causation of multiple sclerosis is that it is an autoimmune disease linked in some way to a viral infection.^{1 , 2} Nonetheless, despite extensive investigation, neither pathogenic autoreactive T cells or antibodies nor a virus has been shown to have a clear role in the disease process.² Clinically, multiple sclerosis may be categorized as being of the exacerbating–remitting type, in which discrete episodes of neurologic dysfunction are followed by recovery, . . .