β-Ketoester Reduction by Baker's Yeast Immobilized in Calcium Alginate: An Examination of pH Effects on Enantiospecificity
- 1 May 1993
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 23 (9), 1201-1208
- https://doi.org/10.1080/00397919308011204
Abstract
Enantiospecificity of the reduction process and product yields in the reduction of ethyl acetoacetate and ethyl benzoylacetate by baker's yeast immobilized in calcium aliginate beads depend strongly on the pH of the medium, and under optimum conditions products with high yields (80–85%) and high optical purity (e.e. 90–99%) can be obtained.Keywords
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