Neoplasia in the vagina following hysterectomy for dysplasia or carcinomain situof the uterine cervix

Abstract

To establish some of the factors responsible for an increased risk of neoplasia in the vagina following primary hysterectomy for dysplasia or carcinoma in situ of the cervix, 63 surgical specimens from patients with subsequent neoplasia in the vagina were compared with specimens from 40 patients without subsequent neoplasia. The frequency of neoplasia in the vagina was when dysplasia or carcinoma in situ could be demonstrated in the vaginal margin. Neither the degree of endocervical glandular involvement, the number of mitoses, nor the inflammatory response of the connective tissue appeared to be significant in this respect. No significant connection was found between the severity of the preinvasive lesion of the cervix and the subsequent neoplasia in the vagina.