Amino acid sequence of the encephalitogenic basic protein from human myelin
- 1 June 1971
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 123 (1), 57-67
- https://doi.org/10.1042/bj1230057
Abstract
Myelin from the central nervous system contains an unusual basic protein, which can induce experimental autoimmune encephalomyelitis. The basic protein from human brain was digested with trypsin and other enzymes and the sequence of the 170 amino acids was determined. The localization of the encephalitogenic determinants was described. Possible roles for the protein in the structure and function of myelin are discussed.Keywords
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