Escherichia coli Hemagglutinin Response of Adult Volunteers to Ingested E. coli 055 B5
- 1 February 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 82 (2), 215-219
- https://doi.org/10.3181/00379727-82-20070
Abstract
The E. coli hemagglutinin response of adult volunteers to ingestion of E. coli 055 and a "normal" strain of E. coli, respectively, was detd. Increase in E. coli 055 hemagglutinin titers was observed in all subjects following administration of living organisms in large numbers and in 2/3 of individuals who received smaller numbers. None of the controls who received milk without E. coli showed such an antibody response, nor did the volunteers who ingested large numbers of killed 055 organisms or viable bacteria of a "normal" strain of E. coli. Good correlation was found between increases of E. coli 055 hemagglutinin titers and the appearance of bacterial 0 agglutinins. The E. coli hemagglutination test proved to be more sensitive than the conventional bacterial agglutination test, inasmuch as the former method with the post-feeding serum specimens yielded antibody titers which were 5-20 times higher and detected antibodies in prefeeding serum specimens which were not demonstrated by the latter method.Keywords
This publication has 5 references indexed in Scilit:
- Inhibition of Bacterial (Escherichia Coli) Modification of ErythrocytesExperimental Biology and Medicine, 1952
- STUDIES ON HEMAGGLUTINATION AND HEMOLYSIS BY ESCHERICHIA COLI ANTISERAThe Journal of Experimental Medicine, 1952
- EXPERIMENTS ON FEEDING ADULT VOLUNTEERS WITH ESCHERICHIA COLI 111, B4, A COLIFORM ORGANISM ASSOCIATED WITH INFANT DIARRHEAAmerican Journal of Epidemiology, 1952
- Demonstration of Escherichia coli 055 and 0111 Antigens by Means of Hemagglutination Test.Experimental Biology and Medicine, 1952
- E. coli Serotype D433: Occurrence in Intestinal and Respiratory Tracts, Cultural Characteristics, Pathogenicity, Sensitivity to Antibiotics.Experimental Biology and Medicine, 1950