PERCENTAGE OF COLLOID AND BEHAVIOUR OF RADIOACTIVE IODINE IN THE CHICK THYROID AFTER STIMULATION WITH TSH

Abstract

The percentage of intrafollicular colloid and the release and uptake of I131 was studied in young, non-pretreated chicks after stimulation with thyrotropin (TSH). When colloid started to decrease 2 hours after injection of TSH and reached a minimum at 24 hours, by 72 hours it had returned to normal. An increased release of Il31 was first seen 8-12 hours after stimulation . reaching a minimum at 12-24 hours and returning to normal at 48 hours. An increase in the uptake of I131 was first seen during the period from 24-48 hours after stimulation. The increase persisted during the 49-72 hour period with a return to normal during the 72-96 hour period.