Chromosome Aberrations Following Irradiation with High-energy Protons and Their Secondary Radiation: A Study of Dose Distribution and Biological Efficiency Using Root-tips of Vicia Faba and Allium Cepa
- 1 January 1960
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 2 (1), 8-19
- https://doi.org/10.1080/09553006014550021
Abstract
Some radiological properties of a 185 mev proton beam were studied with root-tips of bean and onion seedlings. The relationship between dose and number of abnormal metaphases was investigated at different depths of penetration in Lucite. The effect, found in the final part of the range of penetration,was higher than expected when the physical depth-dose to surface-dose ratio is considered. The difference is partly attributed to a variation of the relative biological efficiency. The enhancing effect of oxygen was studied at high and low energies. It was found to be nearly constant. The relative biological efficiency of 170 mev protons as compared with 180 kv roentgen rays for producing chromosome aberrations was found to be 0.7. The chromosome-breaking efficiencies of the secondary radiations from proton-irradiated tissue and brass were studied. The results indicate that the effects of secondary radiation may be neglected in therapeutic procedures.Keywords
This publication has 11 references indexed in Scilit:
- Effects of single dose proton irradiation of normal skin and Vx2 carcinoma in rabbit earsActa Radiologica, 1959
- The Relative Biological Effectiveness of Various Ionizing Radiations in Mammalian SystemsRadiation Research, 1957
- NEUTRONS AND MIXED RADIATIONSPublished by Elsevier ,1956
- Effect of Linear Energy Transfer on Radiation-Induced Chromosome Aberrations in Tradescantia MicrosporesScience, 1954
- The Initiation and Development of Cellular Damage by Ionizing Radiations The Thirty—Second Silvanus Thompson Memorial LectureThe British Journal of Radiology, 1953
- The Concentration of Oxygen Dissolved in Tissues at the Time of Irradiation as a Factor in RadiotherapyThe British Journal of Radiology, 1953
- A Quick-Freeze Method for Making Smear Slides PermanentStain Technology, 1953
- Comparison of the Lethal Effect of Neutrons and Gamma Rays on Mouse Tumours (a) by Irradiation of Grafted Tumoursin vivo, (b) by Irradiation of Tumour Fragmentsin vitroThe British Journal of Radiology, 1948
- Structural changes produced in microspores ofTradescantia by α-radiationJournal of Genetics, 1947