The Mevalonate/Isoprenoid Pathway Inhibitor Apomine (SR-45023A) Is Antiproliferative and Induces Apoptosis Similar to Farnesol
- 1 April 2000
- journal article
- research article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 270 (1), 240-246
- https://doi.org/10.1006/bbrc.2000.2421
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic DevelopmentJournal of Clinical Oncology, 1999
- Farnesyl Protein Transferase Inhibitors and Other Therapies Targeting the Ras Signal Transduction PathwayInvestigational New Drugs, 1999
- 3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors Attenuate Vascular Smooth Muscle Proliferation by Preventing Rho GTPase-induced Down-regulation of p27Published by Elsevier ,1999
- Systematic Review on the Risk and Benefit of Different Cholesterol-Lowering InterventionsArteriosclerosis, Thrombosis, and Vascular Biology, 1999
- Increasing complexity of Ras signalingOncogene, 1998
- Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscleBiochemical Pharmacology, 1996
- Rho as a regulator of the cytoskeletonTrends in Biochemical Sciences, 1995
- Cytotoxicity of Simvastatin to Pancreatic Adenocarcinoma Cells Containing Mutant ras GeneJapanese Journal of Cancer Research, 1994
- Inhibition of Isoprenoid Biosynthesis Induces Apoptosis in Human Promyelocytic HL-60 CellsBiochemical and Biophysical Research Communications, 1994
- Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.Journal of Clinical Investigation, 1985