Effect of Age on Post-Heparin Lipase
- 9 November 1972
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 287 (19), 969-970
- https://doi.org/10.1056/nejm197211092871907
Abstract
A HEPARIN-activated clearing factor, lipoprotein lipase, is considered to have an important role in facilitating the removal of triglycerides from the circulation. The activity of this enzyme is detectable in plasma by an in vitro assay and is commonly called postheparin lipolytic activity (PHLA).Aging has been associated with prolonged alimentary lipemia.1 2 There is also a positive correlation between fasting plasma triglyceride concentrations and age.3 , 4 To define further the effect of age on triglyceride removal, PHLA was measured in a group of elderly subjects.Methods and ResultsPHLA was measured by a modification of the method of Fredrickson, Ono and Davis . . .Keywords
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