This is a description of the methods of the treatment of inoperable and postoperative urologic tuberculosis as it is administered at the Urological Department (James Buchanan Brady Foundation) of the New York Hospital. During the spring of 1926 a special department was established for the investigation and treatment of inoperable and postoperative urologic tuberculosis. This department was established for the following reasons: It had been found that urogenital tuberculosis is an increasingly important part of urologic work. The modern methods of diagnosis, such as the determination of renal function, genito-urinary roentgenologic studies, the wider usage of guinea-pig inoculations, etc., have shown that the genito-urinary tract is a not infrequent site for tuberculosis. It has therefore followed that a larger number of these patients are appearing for care and treatment. The treatment of genito-urinary tuberculosis is essentially surgical when the tuberculous lesion can be entirely extirpated in an individual who is