Neanthes arenaceodentata (Polychaeta: Annelida), a Proposed Cytogenetic Model for Marine Genetic Toxicology
- 31 July 1980
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Fisheries and Aquatic Sciences
- Vol. 37 (8), 1225-1228
- https://doi.org/10.1139/f80-157
Abstract
Genetic toxicants are present in polluted marine environments and may represent a long-term threat to populations of marine organisms. The in vivo application of sister chromatid exchange (SCE) analysis to a marine polychaete worm N. arenaceodentata is detailed. This species exhibits a dose response to mitomycin C (MMC) at concentrations comparable to those eliciting responses in in vivo mammalian systems. A dose of 5 .times. 10-7 mol/l MMC increased the rate of SCE from a baseline frequency of 0.14/chromosome to 0.5/chromosome. The chromosomes of N. arenaceodentata may provide a useful model for identifying and studying the effects of genetic toxicants in marine environments.Keywords
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