A novel germline PALB2 deletion in Polish breast and ovarian cancer patients
Open Access
- 2 February 2010
- journal article
- research article
- Published by Springer Nature in BMC Medical Genetics
- Vol. 11 (1), 20
- https://doi.org/10.1186/1471-2350-11-20
Abstract
PALB2 protein was recently identified as a partner of BRCA1 and BRCA2 which determines their proper function in DNA repair.Keywords
This publication has 22 references indexed in Scilit:
- PALB2 Links BRCA1 and BRCA2 in the DNA-Damage ResponseCurrent Biology, 2009
- Identification of a novel truncating PALB2mutation and analysis of its contribution to early-onset breast cancer in French-Canadian womenBreast Cancer Research, 2007
- A recurrent mutation in PALB2 in Finnish cancer familiesNature, 2007
- The Fanconi anemia pathway and ubiquitinBMC Biochemistry, 2007
- Fanconi anemia is associated with a defect in the BRCA2 partner PALB2Nature Genetics, 2006
- PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility geneNature Genetics, 2006
- Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancerNature Genetics, 2006
- Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2Molecular Cell, 2006
- Molecular pathogenesis of Fanconi anemia: recent progressBlood, 2006
- Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 StudiesAmerican Journal of Human Genetics, 2003