Serum Concentrations of Uric Acid and the Metabolic Syndrome Among US Children and Adolescents

Abstract

Background— The association between concentrations of uric acid and the metabolic syndrome in children and adolescents remains incompletely understood. The objective of this study was to examine how these 2 were associated in a nationally representative sample of US children and adolescents. Methods and Results— We performed a cross-sectional analysis of 1370 males and females aged 12 to 17 years using data from the National Health and Nutrition Examination Survey 1999–2002. The prevalence of the metabolic syndrome was 291.5 to ≤339 μmol/L or >4.9 to ≤5.7 mg/dL) and 14.79 (95% confidence interval, 7.78 to 28.11) for those in the top quartile (>339 μmol/L) aft...