Antiviral Antibiotics: Inhibition of Focus-Formation in Human or Mouse Cell Cultures by Sarcoma-Inducing Oncornaviruses with Rifamycins

Abstract

Some rifamycin antibiotics which do not inhibit the viral DNA polymerase activity of oncornaviruses can nevertheless inhibit formation of foci of transformed cells in human and mouse cell cultures by transforming oncornaviruses through a blockade of an early step in virus infection.