Nonconcentration of Thiocyanate-C14 by the Thyroid Gland of the Mouse
- 31 March 1958
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 193 (1), 83-85
- https://doi.org/10.1152/ajplegacy.1958.193.1.83
Abstract
After administration of C14-labeled thiocyanate, the concentration of C14 in the thyroid gland following equilibration was about half that in the serum of normal and hypophysectomized C3H mice. Paper chromatography of the serum revealed that 90% of the C14 was in the form of thiocyanate. These results, coupled with a previous analysis which indicated that thiocyanate competitively inhibited the thyroid iodide concentrating mechanism, appear to eliminate the possibility that concentrated iodide is held in the thyroid by adsorption.Keywords
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