Oncogene-Induced Cell Senescence — Halting on the Road to Cancer
- 7 September 2006
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 355 (10), 1037-1046
- https://doi.org/10.1056/nejmra062285
Abstract
This review of oncogene-induced cell senescence describes a physiological mechanism that provides protection against cancer. The mechanisms underlying the arrest of growth in benign or premalignant neoplasms have considerable clinical implications.Keywords
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