Selection of biochemically variant clones of human lymphoid cells
- 1 January 1976
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 39 (3), 353-360
- https://doi.org/10.1111/j.1469-1809.1976.tb00140.x
Abstract
Two established clones of human lymphoid cells, Raji and P3HRI, could be cloned in semi-solid agarose-containing medium at high efficiency. Several other human lymphoid cell lines examined cloned poorly if at all under these conditions. Variant clones of Raji and P3HRI resistant to 6-thioguanine, and in the case of Raji also to either 8-azaadenine or 5-bromo-2'-deoxyuridine, were selected and characterized.Keywords
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