OFFICE USE OF THE FROG TEST FOR PREGNANCY

Abstract

The use of the male frog for the determination of pregnancy has been described and discussed frequently during the past four years. Most of the articles concerning the test have been written by pathologists or persons engaged in institutional work or research. Only a few reports have been made by clinicians who engage in obstetric practice and who perform this pregnancy test in their own offices. As a clinician engaged in the practice of obstetrics and gynecology, I wish to report on my experiences with the Rana pipiens test during the past three years. In that time, a total of 450 pregnancy tests were performed in my office on 350 urine and 100 serum samples. The Rana pipiens test for pregnancy is based on the release of sperm in the urinary bladder of male frogs after they have been injected with an adequate amount of chorionic gonadotropin. This amount is