Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
Open Access
- 1 November 1985
- journal article
- research article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 260 (27), 14873-14878
- https://doi.org/10.1016/s0021-9258(17)38654-4
Abstract
No abstract availableThis publication has 21 references indexed in Scilit:
- Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase IIScience, 1984
- Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.Proceedings of the National Academy of Sciences, 1984
- Adenovirus DNA replication in vitro: synthesis of full-length DNA with purified proteins.Proceedings of the National Academy of Sciences of the United States of America, 1983
- Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycinBiochemistry, 1981
- DNA TopoisomerasesAnnual Review of Biochemistry, 1981
- Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogsJournal of Medicinal Chemistry, 1980
- Theoretical aspects of DNA-protein interactions: Co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous latticeJournal of Molecular Biology, 1974
- Camptothecin effects on DNA synthesis in murine leukemia cellsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
- Intracellular degradation of HeLa and adenovirus type 2 DNA induced by camptothecinBiochemical and Biophysical Research Communications, 1971
- Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2Journal of the American Chemical Society, 1966