Prominent Secondary Constrictions in a Pseudodiploid Human Cell Line

Abstract
RPMI 2650 is a pseudodiploid human cancer strain. The chromosomes frequently exhibit multiple prominent secondary constrictions and the constriction patterns appear to characterize particular homologs. Many of the constrictions are at sites previously specified in benign cells. However, some of the changes observed, especially in chromosomes designated 8, 9, and 10, have been hitherto undescribed in human cells.