• 1 January 1980
    • journal article
    • research article
    • Vol. 56 (2), 242-244
Abstract
Topical 5-fluorouracil (5-FU) was suggested as a simple and effective approach to the treatment of carcinoma in situ of the vulva. Patients (12) with carcinoma in situ of the vulva were evaluated and treated with topical 5-FU. Satisfactory results were obtained in 2. The nonresponders subsequently underwent surgical therapy. Follow-up to date has been 93-96 mo. (average 38 mo.). The value of topical 5-FU in the treatment of carcinoma in-situ of the vulva seems to be limited. Its use in vulvar neoplasia is discussed.