Triethylamine Formate Buffer for HPLC-field Desorption Mass Spectrometry of Oligopeptides

Abstract
A triethylamine-formate buffer system for the HPLC analysis of mixtures of oligopeptides is described. The volatility of TEAF facilitates buffer removal for subsequent field desorption-mass spectral qualitative and quantitative analyses. TEAF permits femtomole quantification of somatostatin, is UV transparent and enables high resolution separation of oligopeptide mixtures.