High Performance Liquid Chromatographic Analysis of Fermentation Broths: Cephalosporin C and Tylosin
- 1 October 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 16 (10), 492-495
- https://doi.org/10.1093/chromsci/16.10.492
Abstract
Procedures are described for the analysis of cephalosporin C or tylosin in fermentation broths by high performance liquid chromatography (HPLC). Quantitation of the major components in cephalosporin C broths was done by a system involving separation by an ion-pair technique. Tylosin data were obtained using a reverse phase method. A method of equating uv potency of tylosin to microbiological potency is discussed. A comparison of HPLC with a microbiological method for the determination of tylosin concentration is also made.This publication has 2 references indexed in Scilit:
- High pressure liquid chromatography of the macrolide antibiotic tylosin.The Journal of Antibiotics, 1977
- High performance liquid chromatography of natural products. I. Separation of cephalosporin C derivatives and cephalosporin antibiotics; isolation of cephalosporin C from fermentation broth.The Journal of Antibiotics, 1976