Follicle cells and germ line cells both affect polarity in dicephalic chimeric follicles of Drosophila
- 1 October 1986
- journal article
- Published by Springer Nature in Wilhelm Roux' Archiv für Entwicklungsmechanik der Organismen
- Vol. 195 (8), 527-531
- https://doi.org/10.1007/bf00375894
Abstract
In aberrant egg follicles of the pattern mutant dicephalic (dic) the oocyte is wedged in between two groups of nurse cells, and this condition may give rise to embryos which express anterior traits at both ends. We have analysed the role of the dic genotype of the germ line cells and the surrounding somatic follicle cells in the formation of the dic follicular phenotype. By means of pole cell transplantations into Fs (1) K 1237 hosts (this cell-autonomous mutation causes degeneration of the host's germ line cells early in oogenesis), we constructed chimeras in which either the follicle cells, the germ line cells, or both were homozygous for the dic mutation. In all three combinations the dic phenotype was expressed but not in controls with dic + in both germ line cells and follicular epithelium. Since follicles with the dic phenotype may be produced if either the germ line cells or the follicle cells lack dic + gene activity we suggest that cellular interactions between both cell types are required for the correct positioning of the oocyte at the follicle's posterior pole.Keywords
This publication has 14 references indexed in Scilit:
- F-actin rings are associated with the ring canals of the Drosophila egg chamberExperimental Cell Research, 1985
- Establishment of Polarity in the Insect EggPublished by Elsevier ,1985
- The spatial arrangement of germ line cells in ovarian follicles of the mutantdicephalic inDrosophila melanogasterWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1984
- Clonal analysis of the tissue specificity of recessive female-sterile mutations of Drosophila melanogaster using a dominant female-sterile mutation Fs(1)K1237Developmental Biology, 1983
- Different requirements for homeotic genes in the soma and germ line of DrosophilaCell, 1983
- Entwicklungsgenetische Untersuchungen an Gynandern vonDrosophila melanogasterWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1974
- The potentialities of transplanted early gastrula nuclei ofDrosophila melanogaster. Production of their imago descendants by germ-line transplantationWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1973
- INTERCELLULAR MIGRATION OF CENTRIOLES IN THE GERMARIUM OF DROSOPHILA MELANOGASTER The Journal of cell biology, 1970
- The origin and early differentiation of the egg chamber of Drosophila melanogasterJournal of Morphology, 1966
- Developmental genetic studies on oogenesis inDrosophila melanogasterJournal of Experimental Zoology, 1963