Circadian Periodicity in Neurospora : Alteration by Inhibitors of Cyclic AMP Phosphodiesterase
- 21 November 1975
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 190 (4216), 789-790
- https://doi.org/10.1126/science.173018
Abstract
Three methyl xanthine inhibitors of adenosine 3',5'-monophosphate phosphodiesterase-theophylline, aminophyline, and caffeine-lengthen the period of the circadian conidiation rhythm of Neurospora. The effect are seen in wild-type strains and in three mutant strains with genetically altered period lengths. These results suggest the possible involvement of adenosine 3', 5'-monophosphate in the control of circadian rhythmicity.Keywords
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