The Effect of Chlorhexidine Irrigation of the Bladder in the Rat
- 1 October 1975
- journal article
- Published by Wiley in British Journal of Urology
- Vol. 47 (5), 539-543
- https://doi.org/10.1111/j.1464-410x.1975.tb06257.x
Abstract
Rats' bladders were irrigated with aqueous solutions of chlorhexidine digluconate 1 : 5,000 or 1 : 10,000 for varying periods up to 48 hours. Histologic examination of the bladders showed severe erosive cystitis in a high percentage of cases. It is concluded that chlorhexidine cannot be recommended for prolonged irrigation of the bladder or for instillation during the intermittent catheterisation where chlorhexidine has repeated and prolonged contact with bladder mucosa.Keywords
This publication has 13 references indexed in Scilit:
- Chlorhexidine resistance inProteus mirabilisJournal of Clinical Pathology, 1974
- Initial effects of cyclophosphamide on urinary bladder epithelium in the ratPathology, 1974
- Prevention of urinary tract infection following spinal cord injurySpinal Cord, 1971
- PREVENTION OF URINARY INFECTION FOLLOWING MAJOR VAGINAL SURGERYBJOG: An International Journal of Obstetrics and Gynaecology, 1968
- Prevention of urinary infection by means of closed drainage into a sterile plastic bag.BMJ, 1967
- THE PERMEABILITY OF RAT TRANSITIONAL EPITHELIUMThe Journal of cell biology, 1966
- Cytological aspects of the mode of action of chlorhexidine diacetateJournal of Pharmacy and Pharmacology, 1965
- Prevention of Catheter Infection of Urine in Female PatientsBMJ, 1962
- URINARY INFECTION AFTER COLPORRHAPHY:ITS INCIDENCE, CAUSATION AND PREVENTIONBJOG: An International Journal of Obstetrics and Gynaecology, 1960
- Antiseptics in MidwiferyBMJ, 1956