HISTOPATHOLOGIC CHANGES IN MACAQUES WITH AN ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS)
- 1 January 1983
- journal article
- research article
- Vol. 113 (3), 382-388
Abstract
The histopathology of tissues obtained from 16 macaque monkeys with acquired immunodeficiency syndrome at necropsy was reviewed. Evidence was found in these animals of several opportunistic infections, including cytomegalovirus (CMV), simian virus 40 (SV-40) and noma. A number of other unusual pathologic processes were noted. In 4 animals an array of lymphoproliferative disorders was observed, ranging from multiple nodules of lymphocytes in the kidney, liver and bone marrow, to frank lymphoma. Evidence of retroperitoneal fibrosis was found in 3 animals. Amyloidosis was observed in several animals; in 2 instances it was present only in the mucosa of the small intestine.This publication has 6 references indexed in Scilit:
- Acquired immunodeficiency syndrome in a colony of macaque monkeys.Proceedings of the National Academy of Sciences, 1983
- The Syndrome of Kaposi's Sarcoma and Opportunistic Infections: An Epidemiologically Restricted Disorder of ImmunoregulationAnnals of Internal Medicine, 1982
- Bovine lymphosarcoma.1980
- NOMA NEONATORUM: ITS ÆTIOPATHOGENESISThe Lancet, 1978
- Hexamitiasis in laboratory mice, hamsters, and rats.1974