IS THE STRATUM-CORNEUM OF UNINVOLVED PSORIATIC SKIN ABNORMAL

  • 1 January 1979
    • journal article
    • research article
    • Vol. 59 (85), 95-100
Abstract
Various abnormalities of the uninvolved skin were reported in psoriasis, but there are few studies on abnormalities of the stratum corneum (SC). The intracorneal cohesion and structural detail of corneocytes of the SC from involved and uninvolved sites in 24 patients with psoriasis and 10 controls are examined. Intracorneal cohesion is increased in the involved and uninvolved skin of psoriatic patients compared to controls. There are abnormalities of SC and corneocyte structure as determined by scanning electron microscopy. The changes in the uninvolved sites may be due to the increased rate of epidermal cell production in these areas.