Absence of K cells in human gut mucosa.
Open Access
- 1 April 1978
- Vol. 19 (4), 273-276
- https://doi.org/10.1136/gut.19.4.273
Abstract
Lymphocytes have been isolated from human rectal biopsies in numbers sufficient for microassay procedures. No antibody-dependent cell-mediated cytotoxic (ADCC) activity could be detected in normal or inflamed human gut mucosa, using two assay systems which detect predominantly K cell activity. The tissue localisation and circulation characteristics of K cells require definition before establishing their role as an efferent immunological mechanism.Keywords
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