Cholesterol-Lowering Drugs and Advanced Prostate Cancer Incidence in a Large U.S. Cohort

Abstract

Background: 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors, commonly known as statins, account for the great majority of cholesterol-lowering drug use in the United States. Long-duration statin use was associated with substantially reduced risk of advanced prostate cancer in a recent large prospective study.