The Radiolabeling of Lymphocytes and Tumor Cells with 111Indium

Abstract

Summary ¹¹¹Indium when complexed with oxine is an efficient label of lymphocytes and tumor cells. ¹¹¹Indium-oxine complex (¹¹¹InOx) is not reutilizable, making it useful for short-term lymphocyte recirculation studies. The spontaneous release of ¹¹¹InOx from tumor cells is very low, making it a useful isotope in cytotoxicity studies. ¹¹¹InoX emits two γ photons detectable by nuclear scanning, making this label of potential use in the study of lymphocyte migration in man.