Correction of Postoperative Metabolic Alkalosis and Renal Failure by Hemodialysis

Abstract

Postoperative patients (3) with oliguric renal failure and hypochloremic metabolic alkalosis were treated with hemodialysis using a specially prepared high Cl-, low-acetate dialysate. This mode of therapy corrected the metabolic abnormalities and was significantly more effective than treatment with commercially available high-acetate dialysate at increasing the serum Cl- and H+ concentration and decreasing the serum .**GRAPHIC**. concentration. Furthermore, hemodialysis with high Cl-, low-acetate dialysate corrected the clinical sequelae of hypoventilation, cardiac arrhythmia and neuromuscular irritability associated with metabolic alkalosis while treating uremia simultaneously.