In July, 1923, we published a preliminary report1of observations on the time required for the disappearance of intradermally injected salt solution in six children having edema, and in a small group of control cases including three normal adults. We found that the elevation produced by the injection of 0.2 c.c. of 0.8 per cent, sodium chlorid solution disappeared much more rapidly in the patients with edema than it did in the control cases. We stated that our results suggested that the test might be of value, first, in the detection of disturbed water balance in the tissue, and, secondly, as a means of following the progress of a case in which the presence of such a disturbance had been established. At present we consider that in normal children over 1 year of age the lower limit of the disappearance time is above sixty minutes, when the technic given